(Ivanhoe Newswire) -- You are not in the clear if you suffer from rhinosinusitis (CRS), an inflammatory condition involving the paranasal sinuses. Those who are affected by CRS are more likely to suffer from other chronic illnesses.
A new study suggests patients who suffer from CRS also tend to suffer from asthma, arthritis and asthma-like illnesses. Researchers studied 1,970,695 patients to determine if such a relationship existed. The analysis shows an especially high incidence of CRS in patients with asthma, who are also more likely to have nasal polyps.
Researchers also noted that patients with high blood pressure and arthritis have high incidences of chronic sinusitis. Results of the study suggest these chronic illnesses and chronic rhinosinusitis may share certain mechanisms that influence how they arise or progress.
More than 37 million Americans suffer at least one episode of acute sinusitis each year, according to the American Academy of Otolaryngology -- Head and Neck Surgery. Researchers suggest the prevalence of the condition has risen in the last decade because of urban sprawl, pollution and increased antibiotic resistance.
SOURCE: (AAO-HNSF) Annual Meeting & OTO EXPO, October 4, 2009
-- Steven L. Email: sdlit...@earthlinkNOSPAM.net Remove the NOSPAM before replying to me.
On Oct 6, 8:45 am, "Steven L." <sdlit...@earthlink.net> wrote:
> Chronic Rhinosinusitis Gateway to Other Illnesses
Eh.
For now, I'll just stick with the sinusitis. Odds are ... I'll get bored later and look for another barely manageable condition that takes a good whack at QoL.
In article <c8mdndiq56yexVbXnZ2dnUVZ_tti4...@earthlink.com>, "Steven
L." <sdlit...@earthlink.net> wrote: > A new study suggests patients who suffer from CRS also tend to suffer > from asthma, arthritis and asthma-like illnesses. Researchers studied > 1,970,695 patients to determine if such a relationship existed. The > analysis shows an especially high incidence of CRS in patients with > asthma, who are also more likely to have nasal polyps.
> Researchers also noted that patients with high blood pressure and > arthritis have high incidences of chronic sinusitis. Results of the > study suggest these chronic illnesses and chronic rhinosinusitis may > share certain mechanisms that influence how they arise or progress.
In article <7j1qniF338tp...@mid.individual.net>, Susan
<su...@nothanks.org> wrote: > > Researchers also noted that patients with high blood pressure and > > arthritis have high incidences of chronic sinusitis. Results of the > > study suggest these chronic illnesses and chronic rhinosinusitis may > > share certain mechanisms that influence how they arise or progress.
> They do; HPA axis dysregulation, insulin resistance, inherited hormone > receptor disorders including vit D receptors, AND they get treated with > drugs for years on end that cause rebound diseases and syndromes.
Chronic antibiotic use can lead to dysbiosis - death of friendly gut bacteria in the GI tract or in the sinuses - which then paves the way for overgrowth of competing fungi or pathogenic bacteria. One of the functions of friendly bacteria is to supply butyrate and other short-chain fatty acids while assisting in the digestion of fiber and nutritional absorption. Butyrate, in turn, has epigenetic functions, including upregulation of the dopamine transporter DAT and quinone detoxifier NQO1. These bacteria can also synthesize vitamin K2, which is a regulator of vitamin D and interacts with NQO1/2. It's quite likely just from these pathways that friendly bacteria play a regulatory role in the local sympathetic nerves and, perhaps through them, the HPA response. NQO1/2 polymorphisms are certainly linked to Parkinson's, Crohn's and other types of autoimmunity.
>> A new study suggests patients who suffer from CRS also tend to suffer >> from asthma, arthritis and asthma-like illnesses. Researchers studied >> 1,970,695 patients to determine if such a relationship existed. The >> analysis shows an especially high incidence of CRS in patients with >> asthma, who are also more likely to have nasal polyps.
>> Researchers also noted that patients with high blood pressure and >> arthritis have high incidences of chronic sinusitis. Results of the >> study suggest these chronic illnesses and chronic rhinosinusitis may >> share certain mechanisms that influence how they arise or progress.
> Low vitamin D3 could be a common factor.
both vitamin D2 and D3, in fact.
I've noticed a distinct improvement in my health generally since I've started taking both D2 and D3.
In the past, it was believed that D3 could do everything D2 could do. Now we know that D2 has specialized functions for cells in the bone marrow and elsewhere, a process called "autocrine signaling." (Google for it)
-- Steven L. Email: sdlit...@earthlinkNOSPAM.net Remove the NOSPAM before replying to me.
>> I've noticed a distinct improvement in my health generally since I've >> started taking both D2 and D3.
>> In the past, it was believed that D3 could do everything D2 could do. >> Now we know that D2 has specialized functions for cells in the bone >> marrow and elsewhere, a process called "autocrine signaling." (Google >> for it)
> My endo says patients with kidney disorders need to take calcitriol > rather than ergo or chole forms.
Well, he's only half right.
I have to take calcitriol--the activated form of vitamin D3--because my kidneys are no longer capable of activating the inactivated form. Vitamin D3 is the form needed for the usual functions of building strong bones and teeth.
But vitamin D2--ergocalciferol--can be used *directly* by the bone marrow in the production of red blood cells and other functions, without needing the kidneys to activate it. This alternate process for vitamin D, autocrine signaling, has only been discovered in the last few years--and kidney patients can benefit from it as well. Your endo may not know about this yet.
But I attended a podcast with physicians who are doing the research on it.
-- Steven L. Email: sdlit...@earthlinkNOSPAM.net Remove the NOSPAM before replying to me.
>> I have to take calcitriol--the activated form of vitamin D3--because >> my kidneys are no longer capable of activating the inactivated form. >> Vitamin D3 is the form needed for the usual functions of building >> strong bones and teeth.
>> But vitamin D2--ergocalciferol--can be used *directly* by the bone >> marrow in the production of red blood cells and other functions, >> without needing the kidneys to activate it. This alternate process >> for vitamin D, autocrine signaling, has only been discovered in the >> last few years--and kidney patients can benefit from it as well. Your >> endo may not know about this yet.
>> But I attended a podcast with physicians who are doing the research on >> it.
> My endo is an M.D. with a Ph.D. in pharmacology, chair of his academic > dept. and a full time researcher without a traditional private practice.
And he's still only half right.
-- Steven L. Email: sdlit...@earthlinkNOSPAM.net Remove the NOSPAM before replying to me.
> Chronic Rhinosinusitis Gateway to Other Illnesses
> (Ivanhoe Newswire) -- You are not in the clear if you suffer from > rhinosinusitis (CRS), an inflammatory condition involving the paranasal > sinuses. Those who are affected by CRS are more likely to suffer from > other chronic illnesses.
> A new study suggests patients who suffer from CRS also tend to suffer > from asthma, arthritis and asthma-like illnesses. Researchers studied > 1,970,695 patients to determine if such a relationship existed. The > analysis shows an especially high incidence of CRS in patients with > asthma, who are also more likely to have nasal polyps.
> Researchers also noted that patients with high blood pressure and > arthritis have high incidences of chronic sinusitis. Results of the > study suggest these chronic illnesses and chronic rhinosinusitis may > share certain mechanisms that influence how they arise or progress.
> More than 37 million Americans suffer at least one episode of acute > sinusitis each year, according to the American Academy of Otolaryngology > -- Head and Neck Surgery. Researchers suggest the prevalence of the > condition has risen in the last decade because of urban sprawl, > pollution and increased antibiotic resistance.
> SOURCE: (AAO-HNSF) Annual Meeting & OTO EXPO, October 4, 2009
> -- > Steven L. > Email: sdlit...@earthlinkNOSPAM.net > Remove the NOSPAM before replying to me.
Then there is things like mental confusion when your sinuses back up. Anxiety when you cannot do your work. Depression when you loose your job. Feeling lousy after a poor nights sleep cause your nasal passages are blocked. Increase in URIs cause your mucus membranes are a breeding ground for bacteria. Medical mismanagement? Heart problems? Increase in diabetes? Sick days? etc, etc, etc.
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